BDBM50219679 CHEMBL247645::N-(4-(2,4-difluoro-3-(trifluoromethyl)phenyl)thiazol-2-yl)-4-(pyrimidin-4-ylamino)benzamide

SMILES Fc1ccc(-c2csc(NC(=O)c3ccc(Nc4ccncn4)cc3)n2)c(F)c1C(F)(F)F

InChI Key InChIKey=SYIXSYVLTFSTAU-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50219679   

TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50219679(N-(4-(2,4-difluoro-3-(trifluoromethyl)phenyl)thiaz...)
Affinity DataEC50:  33nMAssay Description:Agonist activity at human TPOr expressed in BaF3 cells by reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThrombopoietin receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50219679(N-(4-(2,4-difluoro-3-(trifluoromethyl)phenyl)thiaz...)
Affinity DataEC50:  33nMAssay Description:Agonist activity at TPO receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed