BDBM50219918 5-(4-((phenethylamino)methyl)phenoxy)picolinamide::CHEMBL236376

SMILES NC(=O)c1ccc(Oc2ccc(CNCCc3ccccc3)cc2)cn1

InChI Key InChIKey=RDWUBDSRHFANBO-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50219918   

TargetMu-type opioid receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50219918(5-(4-((phenethylamino)methyl)phenoxy)picolinamide ...)
Affinity DataKi:  0.440nMAssay Description:Antagonist activity at human mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50219918(5-(4-((phenethylamino)methyl)phenoxy)picolinamide ...)
Affinity DataKi:  1.80nMAssay Description:Antagonist activity at human mu opioid receptor expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50219918(5-(4-((phenethylamino)methyl)phenoxy)picolinamide ...)
Affinity DataKi:  2.90nMAssay Description:Antagonist activity at human delta opioid receptor expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50219918(5-(4-((phenethylamino)methyl)phenoxy)picolinamide ...)
Affinity DataKi:  8.5nMAssay Description:Displacement of [3H]bremazocine from human delta opioid receptor expressed in CHO cells in presence of high sodium by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50219918(5-(4-((phenethylamino)methyl)phenoxy)picolinamide ...)
Affinity DataKi:  9.60nMAssay Description:Antagonist activity at human kappa opioid receptor expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50219918(5-(4-((phenethylamino)methyl)phenoxy)picolinamide ...)
Affinity DataKi:  69nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cells in presence of high sodium by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed