BDBM50219933 CHEMBL238305::N-isopropyl-6-(4-((phenethylamino)methyl)phenoxy)nicotinamide

SMILES CC(C)NC(=O)c1ccc(Oc2ccc(CNCCc3ccccc3)cc2)nc1

InChI Key InChIKey=ATDZZSMIODIYKR-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50219933   

TargetMu-type opioid receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50219933(N-isopropyl-6-(4-((phenethylamino)methyl)phenoxy)n...)
Affinity DataKi:  52nMAssay Description:Antagonist activity at human mu opioid receptor expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50219933(N-isopropyl-6-(4-((phenethylamino)methyl)phenoxy)n...)
Affinity DataKi:  2.41E+3nMAssay Description:Displacement of [3H]bremazocine from human delta opioid receptor expressed in CHO cells in presence of high sodium by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50219933(N-isopropyl-6-(4-((phenethylamino)methyl)phenoxy)n...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cells in presence of high sodium by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed