BDBM50220012 (5R)-3-(3-fluoro-4-pyridin-3-ylphenyl)-5-(1H-1,2,3-triazol-1-ylmethyl)-1,3-oxazolidin-2-one::CHEMBL394864

SMILES Fc1cc(ccc1-c1cccnc1)N1C[C@H](Cn2ccnn2)OC1=O

InChI Key InChIKey=URZMJARQWGKHCG-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50220012   

TargetCytochrome P450 2D6(Human)
Astrazeneca Discovery

Curated by ChEMBL
LigandPNGBDBM50220012((5R)-3-(3-fluoro-4-pyridin-3-ylphenyl)-5-(1H-1,2,3...)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of human recombinant CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Astrazeneca Discovery

Curated by ChEMBL
LigandPNGBDBM50220012((5R)-3-(3-fluoro-4-pyridin-3-ylphenyl)-5-(1H-1,2,3...)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of human recombinant CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Astrazeneca Discovery

Curated by ChEMBL
LigandPNGBDBM50220012((5R)-3-(3-fluoro-4-pyridin-3-ylphenyl)-5-(1H-1,2,3...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Astrazeneca Discovery

Curated by ChEMBL
LigandPNGBDBM50220012((5R)-3-(3-fluoro-4-pyridin-3-ylphenyl)-5-(1H-1,2,3...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Astrazeneca Discovery

Curated by ChEMBL
LigandPNGBDBM50220012((5R)-3-(3-fluoro-4-pyridin-3-ylphenyl)-5-(1H-1,2,3...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed