BDBM50220286 1-((2R,6R)-1-(4-chlorophenylsulfonyl)-6-ethylpiperidin-2-yl)cyclopropyl 4-(3-hydroxypropyl)piperazine-1-carboxylate::CHEMBL236183

SMILES CC[C@@H]1CCC[C@@H](N1S(=O)(=O)c1ccc(Cl)cc1)C1(CC1)OC(=O)N1CCN(CCCO)CC1

InChI Key InChIKey=ZXKFOORTJYGGON-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50220286   

TargetAmyloid-beta precursor protein(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50220286(1-((2R,6R)-1-(4-chlorophenylsulfonyl)-6-ethylpiper...)
Affinity DataIC50: 15nMAssay Description:Inhibition of gamma-secretase assessed as reduction of cell A-beta-40 levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50220286(1-((2R,6R)-1-(4-chlorophenylsulfonyl)-6-ethylpiper...)
Affinity DataIC50: 17nMAssay Description:Inhibition of gamma-secretase assessed as reduction of membrane A-beta-40 levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed