BDBM50220308 CHEMBL237282::N-(amino(3-hydroxypropylamino)methylene)-2-(4-(2-chlorophenyl)-2-(3-methyl-4-propoxyphenyl)thiophen-3-yl)acetamide

SMILES CCCOc1ccc(cc1C)-c1scc(c1CC(=O)NC(=N)NCCCO)-c1ccccc1Cl

InChI Key InChIKey=YECNYEDWHUCAOP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50220308   

TargetBeta-secretase 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50220308(N-(amino(3-hydroxypropylamino)methylene)-2-(4-(2-c...)
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed