BDBM50220651 CHEMBL399147::N,N-dimethyl(2-(naphthalen-1-yl)cyclopropyl)methanamine

SMILES CN(C)CC1CC1c1cccc2ccccc12

InChI Key InChIKey=AEWPIBYOYSOWAL-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50220651   

TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50220651(N,N-dimethyl(2-(naphthalen-1-yl)cyclopropyl)methan...)
Affinity DataIC50: 18nMAssay Description:Inhibition of human SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50220651(N,N-dimethyl(2-(naphthalen-1-yl)cyclopropyl)methan...)
Affinity DataIC50: 170nMAssay Description:Inhibition of human SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50220651(N,N-dimethyl(2-(naphthalen-1-yl)cyclopropyl)methan...)
Affinity DataIC50: 170nMAssay Description:Inhibition of human SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50220651(N,N-dimethyl(2-(naphthalen-1-yl)cyclopropyl)methan...)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50220651(N,N-dimethyl(2-(naphthalen-1-yl)cyclopropyl)methan...)
Affinity DataIC50: 6.80E+4nMAssay Description:Inhibition of NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed