BDBM50220692 (R)-N-((S)-1-(4-(tert-butylcarbamoyl)-4-(cyclopropylmethyl)piperidin-1-yl)-3-(4-fluorophenyl)-1-oxopropan-2-yl)-4-methylpiperazine-2-carboxamide::CHEMBL399474

SMILES CN1CCN[C@H](C1)C(=O)N[C@@H](Cc1ccc(F)cc1)C(=O)N1CCC(CC2CC2)(CC1)C(=O)NC(C)(C)C

InChI Key InChIKey=HEJQNESOIJVHRX-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50220692   

TargetMelanocortin receptor 4(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50220692((R)-N-((S)-1-(4-(tert-butylcarbamoyl)-4-(cycloprop...)
Affinity DataIC50: 840nMAssay Description:Binding affinity to human MC4RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50220692((R)-N-((S)-1-(4-(tert-butylcarbamoyl)-4-(cycloprop...)
Affinity DataEC50:  2.17E+3nMAssay Description:Antagonist activity at human MC4R assessed as stimulation of cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed