BDBM50221225 1-(4-(7-chloro-1H-indol-3-yl)piperidin-1-yl)-3-(5-(methylsulfonyl)-3-(4-(trifluoromethyl)phenyl)-4,5,6,7-tetrahydropyrazolo[4,3-c]pyridin-1-yl)propan-2-ol::CHEMBL269130

SMILES CS(=O)(=O)N1CCc2c(C1)c(nn2CC(O)CN1CCC(CC1)c1c[nH]c2c(Cl)cccc12)-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=NZFCSAPTKKXGJD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50221225   

TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50221225(1-(4-(7-chloro-1H-indol-3-yl)piperidin-1-yl)-3-(5-...)
Affinity DataIC50:  34nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed