BDBM50221420 (S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-N-(4-(6-methyl-3-oxo-3,4-dihydropyrazin-2-yl)butyl)propanamide::CHEMBL392828

SMILES Cc1c[nH]c(=O)c(CCCCNC(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)n1

InChI Key InChIKey=JBAQDPIFUIUCNE-KRWDZBQOSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50221420   

TargetMu-type opioid receptor(Human)
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50221420((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-N-(4-...)
Affinity DataKi:  0.620nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Human)
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50221420((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-N-(4-...)
Affinity DataKi:  74nMAssay Description:Displacement of [3H]deltorphin 2 from delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Guinea pig)
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50221420((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-N-(4-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Agonist activity at mu opioid receptor in guinea pig ileum assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Mouse)
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50221420((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-N-(4-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Agonist activity at delta opioid receptor in mouse vas deferens assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed