BDBM50221677 CHEMBL241211::N-(2-(4-(2,3-dichlorophenyl)piperazin-1-yl)ethyl)-3-(2-phenylethynyl)benzamide

SMILES Clc1cccc(N2CCN(CCNC(=O)c3cccc(c3)C#Cc3ccccc3)CC2)c1Cl

InChI Key InChIKey=IDICUFRCUIOPKM-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50221677   

TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50221677(N-(2-(4-(2,3-dichlorophenyl)piperazin-1-yl)ethyl)-...)
Affinity DataKi:  68nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50221677(N-(2-(4-(2,3-dichlorophenyl)piperazin-1-yl)ethyl)-...)
Affinity DataKi:  1.20E+3nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine receptor D2 long expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50221677(N-(2-(4-(2,3-dichlorophenyl)piperazin-1-yl)ethyl)-...)
Affinity DataKi:  1.40E+3nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine receptor D2 short expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Pig)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50221677(N-(2-(4-(2,3-dichlorophenyl)piperazin-1-yl)ethyl)-...)
Affinity DataKi:  3.10E+3nMAssay Description:Displacement of [3H]SCH 23390 from pig dopamine D1 receptor in porcine striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed