BDBM50221949 1-(4-(3,5-difluorophenyl)-5-(4-(trifluoromethyl)phenyl)-1H-imidazol-2-yl)-4-(3-(trifluoromethyl)pyridin-2-yl)piperazine::CHEMBL401333

SMILES Fc1cc(F)cc(c1)-c1nc([nH]c1-c1ccc(cc1)C(F)(F)F)N1CCN(CC1)c1ncccc1C(F)(F)F

InChI Key InChIKey=KPIMWNCJJPAYBB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50221949   

LigandPNGBDBM50221949(1-(4-(3,5-difluorophenyl)-5-(4-(trifluoromethyl)ph...)
Affinity DataIC50: 35nMAssay Description:Antagonist activity at rat TRPV1 expressed in CHO cells assessed blocking of capsaicin-induced calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50221949(1-(4-(3,5-difluorophenyl)-5-(4-(trifluoromethyl)ph...)
Affinity DataIC50: 85nMpH: 5.0Assay Description:Antagonist activity at rat TRPV1 expressed in CHO cells assessed blocking of acid-induced calcium influx at pH 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed