BDBM50221959 1-(4-phenyl-5-(4-(trifluoromethyl)phenyl)-1H-imidazol-2-yl)-4-(3-(trifluoromethyl)pyridin-2-yl)piperazine::CHEMBL246833

SMILES FC(F)(F)c1ccc(cc1)-c1[nH]c(nc1-c1ccccc1)N1CCN(CC1)c1ncccc1C(F)(F)F

InChI Key InChIKey=VCVGVKFIQIWAMK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50221959   

LigandPNGBDBM50221959(1-(4-phenyl-5-(4-(trifluoromethyl)phenyl)-1H-imida...)
Affinity DataIC50: 107nMAssay Description:Antagonist activity at rat TRPV1 expressed in CHO cells assessed blocking of capsaicin-induced calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50221959(1-(4-phenyl-5-(4-(trifluoromethyl)phenyl)-1H-imida...)
Affinity DataIC50: 216nMpH: 5.0Assay Description:Antagonist activity at rat TRPV1 expressed in CHO cells assessed blocking of acid-induced calcium influx at pH 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed