BDBM50221966 (2S,3S)-2-amino-1-((S)-3-fluoro-3-methylpyrrolidin-1-yl)-3-(4-(4-fluorophenyl)cyclohexyl)butan-1-one::CHEMBL392524

SMILES C[C@H]([C@H](N)C(=O)N1CC[C@](C)(F)C1)C1CCC(CC1)c1ccc(F)cc1

InChI Key InChIKey=BKZNLTGYHSYTIZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50221966   

TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221966((2S,3S)-2-amino-1-((S)-3-fluoro-3-methylpyrrolidin...)
Affinity DataIC50: 12nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221966((2S,3S)-2-amino-1-((S)-3-fluoro-3-methylpyrrolidin...)
Affinity DataIC50: 390nMAssay Description:Inhibition of human DPP4 in presence of 50 % human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221966((2S,3S)-2-amino-1-((S)-3-fluoro-3-methylpyrrolidin...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of human DPP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221966((2S,3S)-2-amino-1-((S)-3-fluoro-3-methylpyrrolidin...)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of human DPP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed