BDBM50221971 (2S,3S)-3-(4-([1,2,4]triazolo[1,5-a]pyridin-5-yl)cyclohexyl)-2-amino-1-(3,3-difluoropyrrolidin-1-yl)butan-1-one::CHEMBL237152

SMILES C[C@H]([C@H](N)C(=O)N1CCC(F)(F)C1)C1CCC(CC1)c1cccc2ncnn12

InChI Key InChIKey=KNWLGOHITUGUED-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50221971   

TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221971((2S,3S)-3-(4-([1,2,4]triazolo[1,5-a]pyridin-5-yl)c...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221971((2S,3S)-3-(4-([1,2,4]triazolo[1,5-a]pyridin-5-yl)c...)
Affinity DataIC50: 28nMAssay Description:Inhibition of human DPP4 in presence of 50 % human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221971((2S,3S)-3-(4-([1,2,4]triazolo[1,5-a]pyridin-5-yl)c...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human DPP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221971((2S,3S)-3-(4-([1,2,4]triazolo[1,5-a]pyridin-5-yl)c...)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of human DPP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed