BDBM50221973 (2S,3S)-3-amino-4-(3,3-difluoropyrrolidin-1-yl)-2-((1s,4R)-4-(2,6-dimethoxypyrimidin-4-yl)cyclohexyl)-N,N-dimethyl-4-oxobutanamide::CHEMBL235004

SMILES COc1cc(nc(OC)n1)[C@@H]1CC[C@@H](CC1)[C@@H]([C@H](N)C(=O)N1CCC(F)(F)C1)C(=O)N(C)C

InChI Key InChIKey=JXNWDCSITWNCHN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50221973   

TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221973((2S,3S)-3-amino-4-(3,3-difluoropyrrolidin-1-yl)-2-...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221973((2S,3S)-3-amino-4-(3,3-difluoropyrrolidin-1-yl)-2-...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human DPP4 in presence of 50 % human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221973((2S,3S)-3-amino-4-(3,3-difluoropyrrolidin-1-yl)-2-...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human DPP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221973((2S,3S)-3-amino-4-(3,3-difluoropyrrolidin-1-yl)-2-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human DPP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed