BDBM50222419 4-biphenyl-2-ylethynyl-6,7-dimethoxy-quinazoline::CHEMBL250924

SMILES COc1cc2ncnc(C#Cc3ccccc3-c3ccccc3)c2cc1OC

InChI Key InChIKey=ZUBUFJOEYHKFCQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50222419   

TargetEpidermal growth factor receptor(Human)
Mitsubishi Pharma

Curated by ChEMBL
LigandPNGBDBM50222419(4-biphenyl-2-ylethynyl-6,7-dimethoxy-quinazoline |...)
Affinity DataIC50: 26nMAssay Description:Inhibition of partially purified EGFR tyrosine kinase from human A431 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed