BDBM50222491 CHEMBL249928::N-(2-(4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)quinazolin-5-yloxy)ethyl)-2-hydroxy-N-methylacetamide
SMILES CN(CCOc1cccc2ncnc(Nc3ccc(OCc4ccccn4)c(Cl)c3)c12)C(=O)CO
InChI Key InChIKey=XNMHWKJRXNZELF-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50222491
Affinity DataIC50: 43nMAssay Description:Inhibition of Erb2 autophosphorylation by cellular clone 24 assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of KdrMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of ErbB2 kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair