BDBM50223440 CHEMBL236040::N-(2-(methylthio)benzyl)-5-((R)-2-((R)-2-hydroxy-2-(4-hydroxy-3-(hydroxymethyl)phenyl)ethylamino)propyl)-1H-indole-2-carboxamide

SMILES CSc1ccccc1CNC(=O)c1cc2cc(C[C@@H](C)NC[C@H](O)c3ccc(O)c(CO)c3)ccc2[nH]1

InChI Key InChIKey=UIZWXVFAIPLAJX-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50223440   

TargetBeta-2 adrenergic receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50223440(N-(2-(methylthio)benzyl)-5-((R)-2-((R)-2-hydroxy-2...)
Affinity DataEC50:  0.0380nMAssay Description:Agonist activity at human recombinant adrenergic beta-2 receptor expressed in CHO cells assessed as elevation in cAMP levelsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed