BDBM50223789 CHEMBL430363::N-(3-chloro-4-trifluoromethylphenyl)-N'-[(3'-deoxythymidin-3'-yl)methyl]thiourea

SMILES Cc1cn([C@H]2C[C@H](CNC(=S)Nc3ccc(Cl)c(c3)C(F)(F)F)[C@@H](CO)O2)c(=O)[nH]c1=O

InChI Key InChIKey=PGLJFXYYGKUBBV-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50223789   

TargetThymidylate kinase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Gent

Curated by ChEMBL
LigandPNGBDBM50223789(N-(3-chloro-4-trifluoromethylphenyl)-N'-[(3'-deoxy...)
Affinity DataKi:  5.00E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis TMPK expressed in Escherichia coli by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThymidylate kinase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Gent

Curated by ChEMBL
LigandPNGBDBM50223789(N-(3-chloro-4-trifluoromethylphenyl)-N'-[(3'-deoxy...)
Affinity DataKi:  5.00E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis TMPK assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed