BDBM50225 1-(4-Chloro-phenyl)-3-(5-pyridin-4-yl-[1,3,4]thiadiazol-2-yl)-urea::1-(4-chlorophenyl)-3-(5-pyridin-4-yl-1,3,4-thiadiazol-2-yl)urea::1-(4-chlorophenyl)-3-[5-(4-pyridyl)-1,3,4-thiadiazol-2-yl]urea::CHEMBL1488371::MLS000559246::SMR000178208::cid_931186

SMILES Clc1ccc(NC(=O)Nc2nnc(s2)-c2ccncc2)cc1

InChI Key InChIKey=OIQSVOVTWPXCTN-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50225   

LigandPNGBDBM50225(1-(4-chlorophenyl)-3-(5-pyridin-4-yl-1,3,4-thiadia...)
Affinity DataIC50: 2.11E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Nikolovska-Coleska, Univer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay
TargetGlycoprotein 42(HHV-4)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM50225(1-(4-chlorophenyl)-3-(5-pyridin-4-yl-1,3,4-thiadia...)
Affinity DataIC50: 1.39E+4nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Theodore Jardetzky; Northw...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay
TargetLow molecular weight phosphotyrosine protein phosphatase(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50225(1-(4-chlorophenyl)-3-(5-pyridin-4-yl-1,3,4-thiadia...)
Affinity DataIC50: 3.07E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetRecQ-like DNA helicase BLM(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50225(1-(4-chlorophenyl)-3-(5-pyridin-4-yl-1,3,4-thiadia...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of BLM (unknown origin) by gel-based DNA unwinding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50225(1-(4-chlorophenyl)-3-(5-pyridin-4-yl-1,3,4-thiadia...)
Affinity DataIC50: 8.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay