BDBM50225037 CHEMBL251352::N-(4-(2-(pyridin-2-ylmethylamino)-6-(4-(trifluoromethyl)phenyl)pyrimidin-4-yloxy)benzo[d]thiazol-2-yl)acetamide

SMILES CC(=O)Nc1nc2c(Oc3cc(nc(NCc4ccccn4)n3)-c3ccc(cc3)C(F)(F)F)cccc2s1

InChI Key InChIKey=VBIIEQVIPARGDE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50225037   

LigandPNGBDBM50225037(N-(4-(2-(pyridin-2-ylmethylamino)-6-(4-(trifluorom...)
Affinity DataIC50: 2.80nMAssay Description:Antagonist activity at rat TRPV1 expressed in CHO cells assessed inhibition of acid induced calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
LigandPNGBDBM50225037(N-(4-(2-(pyridin-2-ylmethylamino)-6-(4-(trifluorom...)
Affinity DataIC50: 5.90nMAssay Description:Antagonist activity at rat TRPV1 expressed in CHO cells assessed inhibition of capsaicin induced calcium influxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed