BDBM50225405 (R)-2-(N-((2-bromopyridin-3-yl)methyl)-4-methoxyphenyl-sulphonamido)-N-hydroxy-3-methylbutanamide::CHEMBL392572

SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1Br)[C@H](C(C)C)C(=O)NO

InChI Key InChIKey=DFWYBNIMFAUWSX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50225405   

Target72 kDa type IV collagenase(Human)
University Hospital of The Westf£Lische Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50225405((R)-2-(N-((2-bromopyridin-3-yl)methyl)-4-methoxyph...)
Affinity DataIC50: 30nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
University Hospital of The Westf£Lische Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50225405((R)-2-(N-((2-bromopyridin-3-yl)methyl)-4-methoxyph...)
Affinity DataIC50: 59nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
University Hospital of The Westf£Lische Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50225405((R)-2-(N-((2-bromopyridin-3-yl)methyl)-4-methoxyph...)
Affinity DataIC50: 75nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
University Hospital of The Westf£Lische Wilhelms-Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50225405((R)-2-(N-((2-bromopyridin-3-yl)methyl)-4-methoxyph...)
Affinity DataIC50: 103nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed