BDBM50226450 (S)-2-amino-6-[2-(3'-methoxybiphenyl-3-yl)ethyl]-3,6-dimethyl-5,6-dihydro-3H-pyrimidin-4-one::CHEMBL239641

SMILES COc1cccc(c1)-c1cccc(CC[C@@]2(C)CC(=O)N(C)C(N)=N2)c1

InChI Key InChIKey=VDFBMQAUECXNKR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50226450   

TargetBeta-secretase 1(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50226450((S)-2-amino-6-[2-(3'-methoxybiphenyl-3-yl)ethyl]-3...)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed