BDBM50226454 2-amino-6-[2-(3'-methoxybiphenyl-3-yl)ethyl]-3,6-dimethyl-5,6-dihydro-3H-pyrimidin-4-one::CHEMBL393911

SMILES COc1cccc(c1)-c1cccc(CCC2(C)CC(=O)N(C)C(N)=N2)c1

InChI Key InChIKey=VDFBMQAUECXNKR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50226454   

TargetBeta-secretase 1(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50226454(2-amino-6-[2-(3'-methoxybiphenyl-3-yl)ethyl]-3,6-d...)
Affinity DataIC50: 200nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50226454(2-amino-6-[2-(3'-methoxybiphenyl-3-yl)ethyl]-3,6-d...)
Affinity DataIC50: 640nMAssay Description:Inhibition of human full length BACE1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed