BDBM50226629 CHEMBL266647::N-(1S-[2-{4-[(2R)-methyl-3-(4-chlorophenyl)propionyl]-1-piperazinyl}-5-chlorophenyl]-3-methylbutyl)-3-(dimethylamino)propionamide
SMILES CC(C)C[C@H](NC(=O)CCN(C)C)c1cc(Cl)ccc1N1CCN(CC1)C(=O)[C@H](C)Cc1ccc(Cl)cc1
InChI Key InChIKey=NICHJJOSEXYBED-AMGIVPHBSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 50226629
Affinity DataKi: 3.40nMAssay Description:Displacement of [125I]NDPMSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Binding affinity to mouse MC4RMore data for this Ligand-Target Pair
Affinity DataKi: 340nMAssay Description:Binding affinity to mouse MC3RMore data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 460nMAssay Description:Binding affinity to GHSRMore data for this Ligand-Target Pair
Affinity DataKi: 600nMAssay Description:Displacement of [125I]NDPMSH from human MC5R expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 710nMAssay Description:Displacement of [125I]NDPMSH from human MC3R expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
Affinity DataIC50: 930nMAssay Description:Antagonist activity at human MC4R expressed in HEK293 cells assessed as inhibition of alpha-MSH-stimulated cAMP productionMore data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataEC50: 720nMAssay Description:Agonist activity at GHSRMore data for this Ligand-Target Pair