BDBM50227562 CHEMBL253820::perfluorobenzyl 6-oxo-1,6-dihydropyridine-2-carboxylate

SMILES Fc1c(F)c(F)c(COC(=O)c2cccc(=O)[nH]2)c(F)c1F

InChI Key InChIKey=SENFKJJTAIUEKU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50227562   

TargetInterstitial collagenase(Human)
North Dakota State University

Curated by ChEMBL
LigandPNGBDBM50227562(perfluorobenzyl 6-oxo-1,6-dihydropyridine-2-carbox...)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
North Dakota State University

Curated by ChEMBL
LigandPNGBDBM50227562(perfluorobenzyl 6-oxo-1,6-dihydropyridine-2-carbox...)
Affinity DataIC50: 6.30E+4nMAssay Description:Inhibition of MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
North Dakota State University

Curated by ChEMBL
LigandPNGBDBM50227562(perfluorobenzyl 6-oxo-1,6-dihydropyridine-2-carbox...)
Affinity DataIC50: 6.40E+4nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
North Dakota State University

Curated by ChEMBL
LigandPNGBDBM50227562(perfluorobenzyl 6-oxo-1,6-dihydropyridine-2-carbox...)
Affinity DataIC50: 6.90E+4nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed