BDBM50228436 2-(2-((dimethylamino)methyl)-4-(3-fluoropropoxy)phenylthio)-5-fluorobenzenamine::CHEMBL239301

SMILES CN(C)Cc1cc(OCCCF)ccc1Sc1ccc(F)cc1N

InChI Key InChIKey=HFHWEFNEZUUCLY-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50228436   

TargetSodium-dependent serotonin transporter(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50228436(2-(2-((dimethylamino)methyl)-4-(3-fluoropropoxy)ph...)
Affinity DataKi:  0.950nMAssay Description:Displacement of [125I]5-iodo-2-[[2,2-[(dimethylamino)methyl]phenyl]thio]benzyl alcohol from SERT expressed in LLCPK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50228436(2-(2-((dimethylamino)methyl)-4-(3-fluoropropoxy)ph...)
Affinity DataKi:  95nMAssay Description:Displacement of [125I]iodonisoxetine from NET expressed in LLCPK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50228436(2-(2-((dimethylamino)methyl)-4-(3-fluoropropoxy)ph...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [125I]N-(3'-iodopropen-2'yl)-2-beta-carbomethoxy-3-beta-(4-chlorophenyl)tropane from DAT expressed in LLCPK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed