BDBM50228553 4-(1-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)-2-oxopiperazine-4-carbonyl)benzonitrile formic acid::CHEMBL239099

SMILES O=C(N1CCN(C(=O)C1)c1ccc(OC2CCN(CC2)C2CCC2)cc1)c1ccc(cc1)C#N

InChI Key InChIKey=IFFOAHBQMKKYRJ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50228553   

TargetCytochrome P450 2D6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50228553(4-(1-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)-2-o...)
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50228553(4-(1-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)-2-o...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50228553(4-(1-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)-2-o...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human CYP3A4 using diethoxyfluorescein substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50228553(4-(1-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)-2-o...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50228553(4-(1-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)-2-o...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human CYP3A4 using 7-benzloxyquinolone substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50228553(4-(1-(4-(1-cyclobutylpiperidin-4-yloxy)phenyl)-2-o...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed