BDBM50228828 1-(oxazolo[4,5-b]pyridin-2-yl)-4-phenylbutan-1-one::CHEMBL257638

SMILES O=C(CCCc1ccccc1)c1nc2ncccc2o1

InChI Key InChIKey=CHYHNCYJTJFWNG-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50228828   

TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50228828(1-(oxazolo[4,5-b]pyridin-2-yl)-4-phenylbutan-1-one...)
Affinity DataKi:  6.90nMAssay Description:Inhibition of rat FAAHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50228828(1-(oxazolo[4,5-b]pyridin-2-yl)-4-phenylbutan-1-one...)
Affinity DataKi:  6.90nMAssay Description:Inhibition of FAAHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50228828(1-(oxazolo[4,5-b]pyridin-2-yl)-4-phenylbutan-1-one...)
Affinity DataKi:  6.90nMAssay Description:Inhibition of FAAHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50228828(1-(oxazolo[4,5-b]pyridin-2-yl)-4-phenylbutan-1-one...)
Affinity DataIC50: 2.24E+3nMAssay Description:Inhibition of full-length human DAGLalpha expressed in HEK293T cell membranes using para-nitrophenylbutyrate by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed