BDBM50230060 4-((S)-2-(benzyloxycarbonyl)-3-((S)-4-(4-(dimethylamino)benzoyl)-3-methylpiperazin-1-yl)-3-oxopropyl)phenyl 4-cyanobenzenesulfonate::CHEMBL403978

SMILES C[C@H]1CN(CCN1C(=O)c1ccc(cc1)N(C)C)C(=O)[C@H](Cc1ccc(OS(=O)(=O)c2ccc(cc2)C#N)cc1)NC(=O)OCc1ccccc1

InChI Key InChIKey=WPBPZBFXKSSNCY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50230060   

TargetP2X purinoceptor 7(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50230060(4-((S)-2-(benzyloxycarbonyl)-3-((S)-4-(4-(dimethyl...)
Affinity DataIC50: 539nMAssay Description:Antagonist activity at human purinergic P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced ethidium bromide uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed