BDBM50230073 (S)-4-(2-(benzyloxycarbonyl)-3-oxo-3-(4-(4-(trifluoromethyl)benzoyl)piperazin-1-yl)propyl)phenyl 4-methylbenzenesulfonate::CHEMBL403897

SMILES Cc1ccc(cc1)S(=O)(=O)Oc1ccc(C[C@H](NC(=O)OCc2ccccc2)C(=O)N2CCN(CC2)C(=O)c2ccc(cc2)C(F)(F)F)cc1

InChI Key InChIKey=GAXYTEBDPNLHNU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50230073   

TargetP2X purinoceptor 7(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50230073((S)-4-(2-(benzyloxycarbonyl)-3-oxo-3-(4-(4-(triflu...)
Affinity DataIC50: 724nMAssay Description:Antagonist activity at human purinergic P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced ethidium bromide uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed