BDBM50230241 CHEMBL252584::{4-[2-((S)-1-amino-3-methyl-butyl)-4-trifluoromethyl-phenyl]-piperazin-1-yl}-[(3S,4S)-4-(4-chloro-phenyl)-1,1-dioxo-tetrahydro-1lambda6-thiophen-3-yl]-methanone

SMILES CC(C)C[C@H](N)c1cc(ccc1N1CCN(CC1)C(=O)[C@H]1CS(=O)(=O)C[C@@H]1c1ccc(Cl)cc1)C(F)(F)F

InChI Key InChIKey=LWZPGHNZXUTEJD-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50230241   

TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50230241({4-[2-((S)-1-amino-3-methyl-butyl)-4-trifluorometh...)
Affinity DataKi:  38nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50230241({4-[2-((S)-1-amino-3-methyl-butyl)-4-trifluorometh...)
Affinity DataIC50: 690nMAssay Description:Antagonist activity at human MC4R assessed as inhibition of alpha MSH-stimulated cAMP release by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed