BDBM50230510 CHEMBL252022::N-{(S)-1-hydroxycarbamoyl-2-[methanesulfonyl-(4-p-tolyloxy-phenyl)-amino]-ethyl}-isobutyramide

SMILES CC(C)C(=O)N[C@@H](CN(c1ccc(Oc2ccc(C)cc2)cc1)S(C)(=O)=O)C(=O)NO

InChI Key InChIKey=HTTNNOVNWHTYRY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50230510   

TargetMatrix metalloproteinase-9(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50230510(N-{(S)-1-hydroxycarbamoyl-2-[methanesulfonyl-(4-p-...)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50230510(N-{(S)-1-hydroxycarbamoyl-2-[methanesulfonyl-(4-p-...)
Affinity DataIC50: 70nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50230510(N-{(S)-1-hydroxycarbamoyl-2-[methanesulfonyl-(4-p-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed