BDBM50230570 CHEMBL4080720

SMILES COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCOP(N)(=O)N(CCCl)CCCl

InChI Key InChIKey=JTZXTHGTQRHIRO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50230570   

TargetEpidermal growth factor receptor(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50230570(CHEMBL4080720)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of recombinant human GST-tagged EGFR cytoplasmic domain (668 to 1210 residues) expressed in baculovirus expression system using Poly (Glu,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2019
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50230570(CHEMBL4080720)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of recombinant human His-tagged HER2 cytoplasmic domain (676 to 1255 residues) expressed in baculovirus expression system using Poly (Glu,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2019
Entry Details Article
PubMed