BDBM50230593 3-(2-amino-6-chloro-pyridin-3-ylmethyl)-5-(2-hydroxy-ethyl)-4-methyl-thiazol-3-ium; chloride::CHEMBL270613::CHEMBL401948

SMILES Cc1c(CCO)sc[n+]1Cc1ccc(Cl)nc1N

InChI Key InChIKey=VVEQGERZHKYNIA-UHFFFAOYSA-N

Data  1 Kd  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50230593   

TargetTransketolase(Human)
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50230593(CHEMBL270613 | CHEMBL401948 | 3-(2-amino-6-chloro-...)
Affinity DataEC50:  9nMAssay Description:Inhibition of transketolase in human HCT116 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetTransketolase(Human)
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50230593(CHEMBL270613 | CHEMBL401948 | 3-(2-amino-6-chloro-...)
Affinity DataEC50:  9nMAssay Description:Inhibition of human transketolase in HCT116 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetTransketolase(Human)
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50230593(CHEMBL270613 | CHEMBL401948 | 3-(2-amino-6-chloro-...)
Affinity DataKd:  46nMAssay Description:Inhibition of transketolase by TPPK/apo-TK coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed