BDBM50230722 CHEMBL4072061

SMILES COc1ncc(cc1NS(=O)(=O)c1ccc(F)cc1F)-c1ccc2ncc(NC(=O)C3CCCCC3)c(OC)c2c1

InChI Key InChIKey=YWHUSKOJKHSUQL-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50230722   

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Hangzhou Xixi Hospital

Curated by ChEMBL

LigandBDBM50230722(CHEMBL4072061)Copy SMILESCopy InChI

Affinity DataIC50: 15nMAssay Description:Inhibition of PI3K p110alpha/p85alpha (unknown origin) using PIP2 as substrate after 1 hr by luminescent kinase-Glo assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/1/2019
Entry Details Article
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