BDBM50230820 CHEMBL253789::c[CO-2,3-pyrazine-CO-D-Nal(2)-Arg-Trp-Lys]-NH2
SMILES NC(N)=NCCC[C@@H]1NC(=O)[C@@H](Cc2ccc3ccccc3c2)NC(=O)c2nccnc2C(=O)NCCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC1=O)C(N)=O
InChI Key InChIKey=YIHQUVPRWHIYHB-SSNHPIBPSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50230820
Affinity DataIC50: 23nMAssay Description:Displacement of [125I][Nle4,D-Phe7]alpha-MSH from human MC3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
University Of Arizona
Curated by ChEMBL
University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 707nMAssay Description:Displacement of [125I][Nle4,D-Phe7]alpha-MSH from human MC1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
University Of Arizona
Curated by ChEMBL
University Of Arizona
Curated by ChEMBL
Affinity DataEC50: >3.00E+3nMAssay Description:Agonist activity at human MC1 receptor expressed in HEK293 cells assessed as intracellular cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Agonist activity at human MC5 receptor expressed in HEK293 cells assessed as intracellular cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [125I][Nle4,D-Phe7]alpha-MSH from human MC4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair