BDBM50231084 5-tert-butyl-2-(4-(1,1,2,2-tetrafluoroethoxy)phenyl)-1H-benzo[d]imidazole::CHEMBL254462

SMILES CC(C)(C)c1ccc2nc([nH]c2c1)-c1ccc(OC(F)(F)C(F)F)cc1

InChI Key InChIKey=HHHJUTSVZVJDHK-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50231084   

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50231084(5-tert-butyl-2-(4-(1,1,2,2-tetrafluoroethoxy)pheny...)Copy SMILESCopy InChI

Affinity DataIC50: 477nMAssay Description:Antagonist activity at human TRPV1 assessed as inhibition of capsaicin-induced calcium influx in HEK293 cellsMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/11/2009
Entry Details Article
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