BDBM50231089 CHEMBL398539::N-((6-methoxy-9-methyl-2,3,4,9-tetrahydro-1H-carbazol-4-yl)methyl)-4-(trifluoromethoxy)benzamide

SMILES COc1ccc2n(C)c3CCCC(CNC(=O)c4ccc(OC(F)(F)F)cc4)c3c2c1

InChI Key InChIKey=WFOZZHQRAQTUTE-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50231089   

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50231089(N-((6-methoxy-9-methyl-2,3,4,9-tetrahydro-1H-carba...)Copy SMILESCopy InChI

Affinity DataIC50: 490nMAssay Description:Antagonist activity at human TRPV1 assessed as inhibition of capsaicin-induced calcium influx in HEK293 cellsMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/11/2009
Entry Details Article
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