BDBM50231335 CHEMBL4105090

SMILES CCOC(=O)c1oc2ccc(NS(=O)(=O)c3ccc(OC)c(OC)c3)cc2c1C

InChI Key InChIKey=VPDKAZOQYIOZHR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50231335   

TargetHypoxia-inducible factor 1-alpha(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50231335(CHEMBL4105090)
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of HIF-1alpha (unknown origin) transcriptional activity expressed in human MCF7 cells after 24 hrs under hypoxic condition by HRE lucifera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2019
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50231335(CHEMBL4105090)
Affinity DataIC50: 1.88E+4nMAssay Description:Inhibition of HIF-1alpha transcriptional activity in human MCF7 cells assessed as reduction in VEGF secretion after 24 hrs under hypoxic condition by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2019
Entry Details Article
PubMed