BDBM50231478 CHEMBL253241::N-{2-[2-[4-(4-acetyl-phenoxy)-phenyl]-5-(3-fluoro-phenyl)-pyrrol-1-yl]-acetyl}-guanidine

SMILES CC(=O)c1ccc(Oc2ccc(cc2)-c2ccc(-c3cccc(F)c3)n2CC(=O)NC(N)=N)cc1

InChI Key InChIKey=FTVUQYFEDAMKHD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50231478   

TargetBeta-secretase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50231478(CHEMBL253241 | N-{2-[2-[4-(4-acetyl-phenoxy)-pheny...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed