BDBM50231646 3-(6-Chloro-naphthalene-2-sulfonyl)-1-[4-(2-hydroxymethyl-1H-imidazo[1,2-a]pyridin-5-yl)-piperazin-1-yl]-propan-1-one::CHEMBL259603::[5-4-{3-[(6-chloronaphthalen-2-yl)sulfonyl]propanoyl}piperazin-1-yl)imidazo[1,2-a]pyridin-2-yl]methanol

SMILES OCc1cn2c(cccc2n1)N1CCN(CC1)C(=O)CCS(=O)(=O)c1ccc2cc(Cl)ccc2c1

InChI Key InChIKey=QHZPAZKNNHHWFB-UHFFFAOYSA-N

Data  4 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50231646   

TargetCoagulation factor X(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50231646([5-4-{3-[(6-chloronaphthalen-2-yl)sulfonyl]propano...)
Affinity DataKi:  8nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50231646([5-4-{3-[(6-chloronaphthalen-2-yl)sulfonyl]propano...)
Affinity DataIC50: 9nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50231646([5-4-{3-[(6-chloronaphthalen-2-yl)sulfonyl]propano...)
Affinity DataIC50: 9.70nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProthrombin(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50231646([5-4-{3-[(6-chloronaphthalen-2-yl)sulfonyl]propano...)
Affinity DataKi:  960nMAssay Description:Inhibition of human thrombin after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetPlasminogen(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50231646([5-4-{3-[(6-chloronaphthalen-2-yl)sulfonyl]propano...)
Affinity DataKi: >6.00E+4nMAssay Description:Inhibition of human plasmin after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50231646([5-4-{3-[(6-chloronaphthalen-2-yl)sulfonyl]propano...)
Affinity DataKi: >6.00E+4nMAssay Description:Inhibition of human tPA after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed