BDBM50231867 CHEMBL4067345

SMILES CN(C)[C@H]1CN(Cc2c(C)cccc2F)C[C@@H]1c1ccc(cc1)N1CCC(CC1)C(=O)N(C)C

InChI Key InChIKey=VROUGOSZOZPFNU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50231867   

TargetPolycomb protein EED(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50231867(CHEMBL4067345)
Affinity DataIC50: 40nMAssay Description:Inhibition of pyrrolidine inhibitor-based oregon-green probe binding to GST-tagged EED (unknown origin) after 1 hr by assay explorer integrated Lanth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed
TargetPolycomb protein EED(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50231867(CHEMBL4067345)
Affinity DataIC50: 70nMAssay Description:Inhibition of pyrrolidine inhibitor-based oregon-green probe binding to GST-tagged EED (unknown origin) after 1 hr by LanthaScreen TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2019
Entry Details Article
PubMed