BDBM50232113 1-(1H-indazol-4-yl)-3-(5-(trifluoromethyl)-2,3-dihydro-1H-inden-1-yl)urea::CHEMBL254866

SMILES FC(F)(F)c1ccc2C(CCc2c1)NC(=O)Nc1cccc2[nH]ncc12

InChI Key InChIKey=QLDCRXZBQVZDEZ-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50232113   

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Abbott Laboratories

Curated by ChEMBL

LigandBDBM50232113(1-(1H-indazol-4-yl)-3-(5-(trifluoromethyl)-2,3-dih...)Copy SMILESCopy InChI

Affinity DataIC50:  3nMAssay Description:Antagonist activity at human TRPV1 assessed as inhibition of calcium influxMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Abbott Laboratories

Curated by ChEMBL

LigandBDBM50232113(1-(1H-indazol-4-yl)-3-(5-(trifluoromethyl)-2,3-dih...)Copy SMILESCopy InChI

Affinity DataIC50:  3nMAssay Description:Blockade of human TRPV1 receptor assessed as inhibition of capsaicin-induced calcium fluxMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI