BDBM50232239 4-(2-chlorophenyl)-9-hydroxy-8-(4-morpholinobutyl)pyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione::CHEMBL403679

SMILES Oc1cc2c(cc1CCCCN1CCOCC1)[nH]c1cc(c3C(=O)NC(=O)c3c21)-c1ccccc1Cl

InChI Key InChIKey=XGLYUVWSAYIXMW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50232239   

TargetWee1-like protein kinase(Human)
Chulalongkorn University

Curated by ChEMBL
LigandPNGBDBM50232239(4-(2-chlorophenyl)-9-hydroxy-8-(4-morpholinobutyl)...)
Affinity DataIC50: 37nMAssay Description:Inhibition of human Wee1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetWee1-like protein kinase(Human)
Chulalongkorn University

Curated by ChEMBL
LigandPNGBDBM50232239(4-(2-chlorophenyl)-9-hydroxy-8-(4-morpholinobutyl)...)
Affinity DataIC50: 37nMAssay Description:Inhibition of human Wee1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50232239(4-(2-chlorophenyl)-9-hydroxy-8-(4-morpholinobutyl)...)
Affinity DataIC50: 71nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50232239(4-(2-chlorophenyl)-9-hydroxy-8-(4-morpholinobutyl)...)
Affinity DataIC50: 250nMAssay Description:Inhibition of human Cdc2 kinase PY15 phosphorylation in HT29 cells by Western blotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed