BDBM50232328 CHEMBL4084996

SMILES Clc1ccc(cc1)-c1nnc(Cc2nc3ccc(Cl)cc3[nH]2)o1

InChI Key InChIKey=AORSHELSJMHDBV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50232328   

TargetEpidermal growth factor receptor(Human)
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50232328(CHEMBL4084996)
Affinity DataIC50: 979nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50232328(CHEMBL4084996)
Affinity DataIC50: 980nMAssay Description:Inhibition of EGF induced EGFR phosphorylation in human KB cells preincubated for 90 mins followed by EGF addition for 5 mins by sandwich ELISA metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Hamdard University

Curated by ChEMBL
LigandPNGBDBM50232328(CHEMBL4084996)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of HRG stimulated erbB2 phosphorylation in human MCF-7 cells preincubated for 90 mins followed by HRG addition for 5 mins by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2019
Entry Details Article
PubMed