BDBM50232352 CHEMBL4073888

SMILES CN(C)Cc1c(C)n(c2ccccc12)S(=O)(=O)c1cccc(\C=C\C(=O)NO)c1

InChI Key InChIKey=SEYPQAFEPPFVGA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50232352   

TargetHistone deacetylase 6(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50232352(CHEMBL4073888)
Affinity DataIC50: 84.9nMAssay Description:Inhibition of full length human recombinant N-terminal GST-tagged HDAC6 expressed in Sf9 cells using RHKK(Ac) as substrate after 90 mins by fluorimet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2019
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50232352(CHEMBL4073888)
Affinity DataIC50: 1.34E+3nMAssay Description:Inhibition of full length human recombinant C-terminal GST-tagged HDAC2 expressed in insect cells using RHKK(Ac) as substrate after 60 mins by fluori...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2019
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50232352(CHEMBL4073888)
Affinity DataIC50: 1.85E+3nMAssay Description:Inhibition of full length human recombinant C-terminal FLAG-His-tagged HDAC1 expressed in Sf21 cells using RHKK(Ac) as substrate after 60 mins by flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2019
Entry Details Article
PubMed