BDBM50232428 CHEMBL4097487

SMILES Cn1cc2cc(ccc2n1)C(=O)Nc1ccc(F)c(F)c1

InChI Key InChIKey=SQQXZJVTMWCPKH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50232428   

TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Ntz Lab

Curated by ChEMBL
LigandPNGBDBM50232428(CHEMBL4097487)
Affinity DataIC50:  38nMAssay Description:Inhibition of recombinant human MAOB expressed in baculovirus-infected BTI insect cells using p-tyramine as substrate measured for 45 mins in presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Ntz Lab

Curated by ChEMBL
LigandPNGBDBM50232428(CHEMBL4097487)
Affinity DataIC50:  221nMAssay Description:Inhibition of MAOB in Sprague-Dawley rat liver mitochondria using p-tyramine as substrate measured for 45 mins in presence of MAOA inhibitor clorgyli...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Ntz Lab

Curated by ChEMBL
LigandPNGBDBM50232428(CHEMBL4097487)
Affinity DataIC50:  764nMAssay Description:Inhibition of recombinant human MAOA expressed in baculovirus-infected BTI insect cells using p-tyramine as substrate measured for 45 mins in presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
Ntz Lab

Curated by ChEMBL
LigandPNGBDBM50232428(CHEMBL4097487)
Affinity DataIC50:  1.88E+3nMAssay Description:Inhibition of MAOA in Sprague-Dawley rat liver mitochondria using p-tyramine as substrate measured for 45 mins in presence of MAOB inhibitor selegili...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed