BDBM50232543 CHEMBL4096216

SMILES C[C@H](NC(=O)c1cc(Cl)cnc1Oc1ccc(F)cc1)c1ccc(cc1)C(O)=O

InChI Key InChIKey=KQRDIJJCEPLGDK-LBPRGKRZSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50232543   

TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50232543(CHEMBL4096216)
Affinity DataIC50:  9.70nMAssay Description:Displacement of [3H]PGE from human EP4 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50232543(CHEMBL4096216)
Affinity DataIC50: >2.00E+4nMAssay Description:Antagonist activity at human EP1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50232543(CHEMBL4096216)
Affinity DataIC50:  26nMAssay Description:Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50232543(CHEMBL4096216)
Affinity DataIC50: >2.00E+4nMAssay Description:Antagonist activity at human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Askat

Curated by ChEMBL
LigandPNGBDBM50232543(CHEMBL4096216)
Affinity DataIC50:  4.36E+3nMAssay Description:Antagonist activity at human EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed